Glutathione peroxidase (GPx) regulates cellular peroxide levels through glutathione oxidation. GPx-mimics based on 4,5-disubstituted fluorene diselenides, their oxides, and ditellurides show catalytic activities consistent with conformational restriction about the dichalcogen bond
Glutathione peroxidase mimics based on conformationally-restricted, peri-like, 4,5-disubstituted fluorene dichalcogenides / Kesar Jagdev, Damiano Tanini, Jack W. Lownes, Carlotta Figliola, Louise Male, Antonella Capperucci, Richard S. Grainger. - In: ORGANIC & BIOMOLECULAR CHEMISTRY. - ISSN 1477-0520. - ELETTRONICO. - 19:(2021), pp. 10565-10569. [10.1039/d1ob02153b]
Glutathione peroxidase mimics based on conformationally-restricted, peri-like, 4,5-disubstituted fluorene dichalcogenides
Damiano Tanini;Antonella Capperucci;
2021
Abstract
Glutathione peroxidase (GPx) regulates cellular peroxide levels through glutathione oxidation. GPx-mimics based on 4,5-disubstituted fluorene diselenides, their oxides, and ditellurides show catalytic activities consistent with conformational restriction about the dichalcogen bond
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