We present an innovative approach allowing the identification, isolation, and molecular characterization of disease-related exosomes based on their different antigenic reactivities. The designed strategy could be immediately translated into any disease in which exosomes are involved. The identification of specific markers and their subsequent association with exosome subtypes, together with the possibility to engineer target-guided exosome-like particles, could represent the key for the effective adoption of exosomes in clinical practice.

A novel phage display based platform for exosome diversity characterization / Maisano, Domenico; Mimmi, Selena; Dattilo, Vincenzo; Marino, Fabiola; Gentile, Massimo; Vecchio, Eleonora; Fiume, Giuseppe; Nisticò, Nancy; Aloisio, Annamaria; de Santo, Maria Penelope; Desiderio, Giovanni; Musolino, Vincenzo; Nucera, Saverio; Sbrana, Francesca; Andò, Sebastiano; Ferrero, Simone; Morandi, Andrea; Bertoni, Francesco; Quinto, Ileana; Iaccino, Enrico. - In: NANOSCALE. - ISSN 2040-3364. - ELETTRONICO. - (2022), pp. 0-0. [10.1039/d1nr06804k]

A novel phage display based platform for exosome diversity characterization

Sbrana, Francesca;Morandi, Andrea;
2022

Abstract

We present an innovative approach allowing the identification, isolation, and molecular characterization of disease-related exosomes based on their different antigenic reactivities. The designed strategy could be immediately translated into any disease in which exosomes are involved. The identification of specific markers and their subsequent association with exosome subtypes, together with the possibility to engineer target-guided exosome-like particles, could represent the key for the effective adoption of exosomes in clinical practice.
2022
0
0
Maisano, Domenico; Mimmi, Selena; Dattilo, Vincenzo; Marino, Fabiola; Gentile, Massimo; Vecchio, Eleonora; Fiume, Giuseppe; Nisticò, Nancy; Aloisio, Annamaria; de Santo, Maria Penelope; Desiderio, Giovanni; Musolino, Vincenzo; Nucera, Saverio; Sbrana, Francesca; Andò, Sebastiano; Ferrero, Simone; Morandi, Andrea; Bertoni, Francesco; Quinto, Ileana; Iaccino, Enrico
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1256169
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