Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity

Kyrousi, Christina; Adam, C O'Neill; Brazovskaja, Agnieska; Zhisong, He; Kielkowski, Pavel; Coquand, Laure; Rossella Di Giaimo,; Pierpaolo D' Andrea,; Belka, Alexander; Andrea Forero Echeverry,; Mei, Davide; Lenge, Matteo; Cruceanu, Cristiana; Isabel, Y Buchsbaum; Khattak, Shahryar; Fabien, Guimiot; Binder, Elisabeth; Elmslie, Frances; Guerrini, Renzo; Alexandre, D Baffet; Stephan, A Sieber; Treutlein, Barbara; Stephen, P Robertson; Cappello, Silvia

doi:10.1038/s41467-021-26447-w

Basal progenitors (BPs), including intermediate progenitors and basal radial glia, are generated from apical radial glia and are enriched in gyrencephalic species like humans, contributing to neuronal expansion. Shortly after generation, BPs delaminate towards the subventricular zone, where they further proliferate before differentiation

Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity / Christina Kyrousi , Adam C O'Neill , Agnieska Brazovskaja , Zhisong He , Pavel Kielkowski , Laure Coquand , Rossella Di Giaimo , Pierpaolo D' Andrea , Alexander Belka , Andrea Forero Echeverry , Davide Mei , Matteo Lenge, Cristiana Cruceanu , Isabel Y Buchsbaum , Shahryar Khattak , Guimiot Fabien , Elisabeth Binder, Frances Elmslie , Renzo Guerrini , Alexandre D Baffet , Stephan A Sieber , Barbara Treutlein , Stephen P Robertson , Silvia Cappello. - In: NATURE COMMUNICATIONS. - ISSN 2041-1723. - ELETTRONICO. - (2021), pp. 0-0. [10.1038/s41467-021-26447-w]