Background: Analyses of few gene-sets in epilepsy showed a potential to unravel key disease associations. We set out to investigate the burden of ultra-rare variants (URVs) in a comprehensive range of biologically informed gene-sets presumed to be implicated in epileptogenesis.
Distinct gene-set burden patterns underlie common generalized and focal epilepsies / Mahmoud Koko , Roland Krause , Thomas Sander , Dheeraj Reddy Bobbili , Michael Nothnagel , Patrick May , Holger Lerche , Epi25 Collaborative, Renzo Guerrini. - In: EBIOMEDICINE. - ISSN 2352-3964. - ELETTRONICO. - 72:(2021), pp. 0-0. [10.1016/j.ebiom.2021.103588]
Distinct gene-set burden patterns underlie common generalized and focal epilepsies
Renzo Guerrini
2021
Abstract
Background: Analyses of few gene-sets in epilepsy showed a potential to unravel key disease associations. We set out to investigate the burden of ultra-rare variants (URVs) in a comprehensive range of biologically informed gene-sets presumed to be implicated in epileptogenesis.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
PIIS2352396421003819.pdf
accesso aperto
Tipologia:
Pdf editoriale (Version of record)
Licenza:
Open Access
Dimensione
2.87 MB
Formato
Adobe PDF
|
2.87 MB | Adobe PDF |
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
