Prospective study on incidence, risk factors and outcome of recurrent clostridioides difficile infections

Granata, G.; Petrosillo, N.; Adamoli, L.; Bartoletti, M.; Bartoloni, A.; Basile, G.; Bassetti, M.; Bonfanti, P.; Borromeo, R.; Ceccarelli, G.; De Luca, A. M.; Di Bella, S.; Fossati, S.; Franceschini, E.; Gentile, I.; Giacobbe, D. R.; Giacometti, E.; Ingrassia, F.; Lagi, F.; Lobreglio, G.; Lombardi, A.; Lupo, L. I.; Luzzati, R.; Maraolo, A. E.; Mikulska, M.; Mondelli, M. U.; Mularoni, A.; Mussini, C.; Oliva, A.; Pandolfo, A.; Rogati, C.; Trapani, F. F.; Venditti, M.; Viale, P.; Caraffa, E.; Cataldo, M. A.

doi:10.3390/jcm10051127

Background: Limited and wide-ranging data are available on the recurrent Clostridioides difficile infection (rCDI) incidence rate. Methods: We performed a cohort study with the aim to assess the incidence of and risk factors for rCDI. Adult patients with a first CDI, hospitalized in 15 Italian hospitals, were prospectively included and followed-up for 30 d after the end of antimicrobial treatment for their first CDI. A case–control study was performed to identify risk factors associated

Prospective study on incidence, risk factors and outcome of recurrent clostridioides difficile infections / Granata G., Petrosillo N., Adamoli L., Bartoletti M., Bartoloni A., Basile G., Bassetti M., Bonfanti P., Borromeo R., Ceccarelli G., De Luca A.M., Di Bella S., Fossati S., Franceschini E., Gentile I., Giacobbe D.R., Giacometti E., Ingrassia F., Lagi F., Lobreglio G., et al.. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - ELETTRONICO. - 10:(2021), pp. 1-11. [10.3390/jcm10051127]