The reduction of aromatic nitro compounds has been performed employing a catalytic amount of Wang resin supported phenyl(2-quinolyl)methanol (Wang-PQM) in the presence of an excess of NaBH4 to regenerate the reactive reducing species at the end of the process. The reduction products are easily isolated through a simple filtration/extraction protocol, and the catalyst can be efficiently recovered and recycled. The condensation route is generally preferred, and azo- and/or hydrazoarenes can be easily prepared in high yields.

Organocatalytic reduction of aromatic nitro compounds: the use of solid-supported phenyl(2-quinolyl)methanol / Donatella Giomi, Jacopo Ceccarelli, Antonella Salvini, Marika Pinto, and Alberto Brandi. - In: ACS OMEGA. - ISSN 2470-1343. - ELETTRONICO. - 7:(2022), pp. 35170-35179. [10.1021/acsomega.2c04196]

Organocatalytic reduction of aromatic nitro compounds: the use of solid-supported phenyl(2-quinolyl)methanol

Donatella Giomi
;
Jacopo Ceccarelli
;
Antonella Salvini;Marika Pinto;
2022

Abstract

The reduction of aromatic nitro compounds has been performed employing a catalytic amount of Wang resin supported phenyl(2-quinolyl)methanol (Wang-PQM) in the presence of an excess of NaBH4 to regenerate the reactive reducing species at the end of the process. The reduction products are easily isolated through a simple filtration/extraction protocol, and the catalyst can be efficiently recovered and recycled. The condensation route is generally preferred, and azo- and/or hydrazoarenes can be easily prepared in high yields.
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35170
35179
Donatella Giomi, Jacopo Ceccarelli, Antonella Salvini, Marika Pinto, and Alberto Brandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2158/1282073
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