Epilepsy is one of the most common brain disorder and, despite the possible use of several therapeutic options, many patients continue to have seizures for their entire lifespan and they need new therapeutic approaches. In the last years the interest on the non-psychoactive compounds present in Cannabis sativa has massively increased, and cannabidiol (CBD) has been shown to be effective in the treatment of different types of neurological disorders and neurodegenerative diseases such as epilepsy, ischemia, multiple sclerosis and Alzheimer's Disease.

Cannabidiol inhibits microglia activation and mitigates neuronal damage induced by kainate in an in-vitro seizure model / Landucci, Elisa; Mazzantini, Costanza; Lana, Daniele; Calvani, Maura; Magni, Giada; Giovannini, Maria Grazia; Pellegrini-Giampietro, Domenico E. - In: NEUROBIOLOGY OF DISEASE. - ISSN 1095-953X. - STAMPA. - 174:(2022), pp. 105895-105895. [10.1016/j.nbd.2022.105895]

Cannabidiol inhibits microglia activation and mitigates neuronal damage induced by kainate in an in-vitro seizure model

Landucci, Elisa
;
Mazzantini, Costanza;Lana, Daniele;Calvani, Maura;Magni, Giada;Giovannini, Maria Grazia;Pellegrini-Giampietro, Domenico E
2022

Abstract

Epilepsy is one of the most common brain disorder and, despite the possible use of several therapeutic options, many patients continue to have seizures for their entire lifespan and they need new therapeutic approaches. In the last years the interest on the non-psychoactive compounds present in Cannabis sativa has massively increased, and cannabidiol (CBD) has been shown to be effective in the treatment of different types of neurological disorders and neurodegenerative diseases such as epilepsy, ischemia, multiple sclerosis and Alzheimer's Disease.
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105895
105895
Landucci, Elisa; Mazzantini, Costanza; Lana, Daniele; Calvani, Maura; Magni, Giada; Giovannini, Maria Grazia; Pellegrini-Giampietro, Domenico E
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2158/1284570
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