We report on the third Assisi Think Tank Meeting (ATTM) on breast cancer, a brainstorming project which involved European radiation and clinical oncologists who were dedicated to breast cancer research and treatment. Held on February 2020, the ATTM aimed at identifying key clinical questions in current clinical practice and “grey” areas requiring research to improve management and outcomes. Before the meeting, three key topics were selected: 1) managing patients with frailty due to either age and/or multi-morbidity; 2) stereotactic radiation therapy and systemic therapy in the management of oligometastatic disease; 3) contralateral breast tumour prevention in BCRA-mutated patients. Clinical practice in these areas was investigated by means of an online questionnaire. In the lapse period between the survey and the meeting, the working groups reviewed data, on-going studies and the clinical challenges which were then discussed in-depth and subjected to intense brainstorming during the meeting; research protocols were also proposed. Methodology, outcome of discussions, conclusions and study proposals are summarized in the present paper. In conclusion, this report presents an in-depth analysis of the state of the art, grey areas and controversies in breast cancer radiation therapy and discusses how to confront them in the absence of evidence-based data to guide clinical decision-making.

Ways to improve breast cancer patients' management and clinical outcome: The 2020 Assisi Think Tank Meeting / Aristei C.; Bolukbasi Y.; Kaidar-Person O.; Pfeffer R.; Arenas M.; Boersma L.J.; Ciabattoni A.; Coles C.E.; Franco P.; Krengli M.; Leonardi M.C.; Marazzi F.; Masiello V.; Meattini I.; Montero A.; Offersen B.; Trigo M.L.; Bourgier C.; Genovesi D.; Kouloulias V.; Morganti A.G.; Meduri B.; Pasinetti N.; Pedretti S.; Perrucci E.; Rivera S.; Tombolini V.; Vidali C.; Valentini V.; Poortmans P.. - In: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. - ISSN 1040-8428. - ELETTRONICO. - 177:(2022), pp. 103774.0-103774.0. [10.1016/j.critrevonc.2022.103774]

Ways to improve breast cancer patients' management and clinical outcome: The 2020 Assisi Think Tank Meeting

Ciabattoni A.;Meattini I.;Valentini V.;
2022

Abstract

We report on the third Assisi Think Tank Meeting (ATTM) on breast cancer, a brainstorming project which involved European radiation and clinical oncologists who were dedicated to breast cancer research and treatment. Held on February 2020, the ATTM aimed at identifying key clinical questions in current clinical practice and “grey” areas requiring research to improve management and outcomes. Before the meeting, three key topics were selected: 1) managing patients with frailty due to either age and/or multi-morbidity; 2) stereotactic radiation therapy and systemic therapy in the management of oligometastatic disease; 3) contralateral breast tumour prevention in BCRA-mutated patients. Clinical practice in these areas was investigated by means of an online questionnaire. In the lapse period between the survey and the meeting, the working groups reviewed data, on-going studies and the clinical challenges which were then discussed in-depth and subjected to intense brainstorming during the meeting; research protocols were also proposed. Methodology, outcome of discussions, conclusions and study proposals are summarized in the present paper. In conclusion, this report presents an in-depth analysis of the state of the art, grey areas and controversies in breast cancer radiation therapy and discusses how to confront them in the absence of evidence-based data to guide clinical decision-making.
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Goal 3: Good health and well-being
Aristei C.; Bolukbasi Y.; Kaidar-Person O.; Pfeffer R.; Arenas M.; Boersma L.J.; Ciabattoni A.; Coles C.E.; Franco P.; Krengli M.; Leonardi M.C.; Marazzi F.; Masiello V.; Meattini I.; Montero A.; Offersen B.; Trigo M.L.; Bourgier C.; Genovesi D.; Kouloulias V.; Morganti A.G.; Meduri B.; Pasinetti N.; Pedretti S.; Perrucci E.; Rivera S.; Tombolini V.; Vidali C.; Valentini V.; Poortmans P.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2158/1285496
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