In conclusion, this pilot analysis seems to support the hypothesis that AF is independently associated with endothelial dysfunction, as expressed by reduced arginine plasma levels. This condition worsening atrial cardiomyopathy and left atrium remodeling could augment the incidence of thromboembolic complications. Importantly, age, synergistically interacting with AF, could further increase the risk profile of patients. Specific studies with an adequate sample size should address these issues to prevent arrhythmia-related morbidity, disability and mortality.

Arginine in older patients with persistent atrial fibrillation: A link to endothelial dysfunction? / Fumagalli, Stefano; Ricciardi, Giulia; Di Serio, Claudia; La Marca, Giancarlo; Marchionni, Niccolò. - In: EUROPEAN JOURNAL OF INTERNAL MEDICINE. - ISSN 0953-6205. - ELETTRONICO. - (2022), pp. 1-3. [10.1016/j.ejim.2022.10.017]

Arginine in older patients with persistent atrial fibrillation: A link to endothelial dysfunction?

Fumagalli, Stefano;Ricciardi, Giulia;Di Serio, Claudia;La Marca, Giancarlo;Marchionni, Niccolò
2022

Abstract

In conclusion, this pilot analysis seems to support the hypothesis that AF is independently associated with endothelial dysfunction, as expressed by reduced arginine plasma levels. This condition worsening atrial cardiomyopathy and left atrium remodeling could augment the incidence of thromboembolic complications. Importantly, age, synergistically interacting with AF, could further increase the risk profile of patients. Specific studies with an adequate sample size should address these issues to prevent arrhythmia-related morbidity, disability and mortality.
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Goal 3: Good health and well-being
Fumagalli, Stefano; Ricciardi, Giulia; Di Serio, Claudia; La Marca, Giancarlo; Marchionni, Niccolò
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2158/1286225
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