Mepolizumab, an anti-interleukin-5 (IL-5) antibody, reduces disease flares in patients with hypereosinophilic syndrome (HES). Factors predicting treatment response are unknown.
Mepolizumab Reduces Hypereosinophilic Syndrome Flares Irrespective of Blood Eosinophil Count and Interleukin-5 / Rothenberg, Marc E; Roufosse, Florence; Faguer, Stanislas; Gleich, Gerald J; Steinfeld, Jonathan; Yancey, Steven W; Mavropoulou, Eleni; Kwon, Namhee, HES Mepolizumab Study Group: Gabriel Ricardo García, Adriana Sosso, Luis Wehbe, Anahí Yañez, Daniël Blockmans, Florence Roufosse, Martti Anton Antila, Daniela Blanco, Sergio Grava, Marina Andrade Lima, Andreia Luisa Francisco Pez, Stanislas Faguer, Mohamed A Hamidou, Jean-Emmanuel Kahn, Guillaume Lefévre, Knut Brockow, Peter M Kern, Andreas J Reiter, Bastian Walz, Tobias Welte, Fabrizio Pane, Alessandro M Vannucchi, Ruth Cerino-Javier, Alfredo Gazca-Aguilar, Dante D Hernández-Colín, Héctor Glenn Valdéz-López, Izabela R Kupryś-Lipińska, Jacek Musial, Witold Prejzner, Eniko Mihaly, Viola Popov, Mihnea Tudor Zdrenghea, Sergey V Gritsaev, Vladimir Ivanov, Nikolay Tsyba, Aránzazu Alonso, Maria Cinta Cid Xutgla, Maria Laura Fox, Regina Garcia Delgado, Jesús María Hernández Rivas, Guillermo Sanz Santillana, Ana Isabel González, Andrew J Wardlaw, Praveen Akuthota, Joseph H Butterfield, Geoffrey L Chupp, John B Cox, Gerald J Gleich, Devi Jhaveri, Marc E Rothenberg. - In: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. IN PRACTICE. - ISSN 2213-2198. - ELETTRONICO. - 10:(2022), pp. 2367-2374.e3. [10.1016/j.jaip.2022.04.037]
Mepolizumab Reduces Hypereosinophilic Syndrome Flares Irrespective of Blood Eosinophil Count and Interleukin-5
Alessandro M Vannucchi;
2022
Abstract
Mepolizumab, an anti-interleukin-5 (IL-5) antibody, reduces disease flares in patients with hypereosinophilic syndrome (HES). Factors predicting treatment response are unknown.File | Dimensione | Formato | |
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