Approved systemic therapies for advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs) have shown limited capacity to reduce tumor burden and no antitumor activity after progression to targeted agents (TAs). We investigated the efficacy and safety of lenvatinib in patients with previously treated advanced GEP-NETs.

Lenvatinib in Patients With Advanced Grade 1/2 Pancreatic and Gastrointestinal Neuroendocrine Tumors: Results of the Phase II TALENT Trial (GETNE1509) / Capdevila, Jaume; Fazio, Nicola; Lopez, Carlos; Teulé, Alexandre; Valle, Juan W; Tafuto, Salvatore; Custodio, Ana; Reed, Nicholas; Raderer, Markus; Grande, Enrique; Garcia-Carbonero, Rocio; Jimenez-Fonseca, Paula; Hernando, Jorge; Bongiovanni, Alberto; Spada, Francesca; Alonso, Vicente; Antonuzzo, Lorenzo; Spallanzani, Andrea; Berruti, Alfredo; La Casta, Adelaida; Sevilla, Isabel; Kump, Patrizia; Giuffrida, Dario; Merino, Xavier; Trejo, Lorena; Gajate, Pablo; Matos, Ignacio; Lamarca, Angela; Ibrahim, Toni. - In: JOURNAL OF CLINICAL ONCOLOGY. - ISSN 1527-7755. - STAMPA. - 39:(2021), pp. 2304-2312. [10.1200/JCO.20.03368]

Lenvatinib in Patients With Advanced Grade 1/2 Pancreatic and Gastrointestinal Neuroendocrine Tumors: Results of the Phase II TALENT Trial (GETNE1509)

Antonuzzo, Lorenzo;Giuffrida, Dario;
2021

Abstract

Approved systemic therapies for advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs) have shown limited capacity to reduce tumor burden and no antitumor activity after progression to targeted agents (TAs). We investigated the efficacy and safety of lenvatinib in patients with previously treated advanced GEP-NETs.
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Capdevila, Jaume; Fazio, Nicola; Lopez, Carlos; Teulé, Alexandre; Valle, Juan W; Tafuto, Salvatore; Custodio, Ana; Reed, Nicholas; Raderer, Markus; Grande, Enrique; Garcia-Carbonero, Rocio; Jimenez-Fonseca, Paula; Hernando, Jorge; Bongiovanni, Alberto; Spada, Francesca; Alonso, Vicente; Antonuzzo, Lorenzo; Spallanzani, Andrea; Berruti, Alfredo; La Casta, Adelaida; Sevilla, Isabel; Kump, Patrizia; Giuffrida, Dario; Merino, Xavier; Trejo, Lorena; Gajate, Pablo; Matos, Ignacio; Lamarca, Angela; Ibrahim, Toni
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2158/1287007
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