Fibroblasts play a crucial role in wound healing and skin fibrosis. It is also probably the cell model used to study in vitro photobiomodulation. Our previous in vivo results evidenced a 19 faster recovery in blue light-treated wounds (410-430 nm). In vitro experiments demonstrated that 20 the lower dose increases cell metabolism, while higher doses (30.9 and 41.2 J/cm2) reduce it. Furthermore, 20.6 J/cm2 affects outward currents and Cytochrome C. Here, we described our preliminary results on the effects of blue LED light on mitochondria and reactive oxygen species production. Globally, our results demonstrated that short-wavelength blue LED light has PBM properties.

Effects of short-wavelength blue light on fibroblasts. Experimental evidence in wound healing and cutaneous fibrosis / Giada Magni, Federica Cherchi, Martina Banchelli, Francesca Tatini, Patrizia Nardini, Daniele Guasti, Elisabetta Coppi, Anna Maria Pugliese, Marco Fraccalvieri, Stefano Bacci, Francesca Rossi. - In: MEDICAL SCIENCES FORUM. - ISSN 2673-9992. - STAMPA. - (2023), pp. 1-6. (Intervento presentato al convegno The 2nd International Electronic Conference on Biomedicines session Wound Healing) [10.3390/ECB2023-14268].

Effects of short-wavelength blue light on fibroblasts. Experimental evidence in wound healing and cutaneous fibrosis

Giada Magni
Conceptualization
;
Federica Cherchi
Membro del Collaboration Group
;
Martina Banchelli
Membro del Collaboration Group
;
Patrizia Nardini
Membro del Collaboration Group
;
Daniele Guasti
Membro del Collaboration Group
;
Elisabetta Coppi
Membro del Collaboration Group
;
Anna Maria Pugliese
Membro del Collaboration Group
;
Stefano Bacci
Membro del Collaboration Group
;
2023

Abstract

Fibroblasts play a crucial role in wound healing and skin fibrosis. It is also probably the cell model used to study in vitro photobiomodulation. Our previous in vivo results evidenced a 19 faster recovery in blue light-treated wounds (410-430 nm). In vitro experiments demonstrated that 20 the lower dose increases cell metabolism, while higher doses (30.9 and 41.2 J/cm2) reduce it. Furthermore, 20.6 J/cm2 affects outward currents and Cytochrome C. Here, we described our preliminary results on the effects of blue LED light on mitochondria and reactive oxygen species production. Globally, our results demonstrated that short-wavelength blue LED light has PBM properties.
2023
2nd International Electronic Conference on Biomedicines, 1–31 March 2023; Available online: https://ecb2023.sciforum.net.
The 2nd International Electronic Conference on Biomedicines session Wound Healing
Goal 4: Quality education
Giada Magni, Federica Cherchi, Martina Banchelli, Francesca Tatini, Patrizia Nardini, Daniele Guasti, Elisabetta Coppi, Anna Maria Pugliese, Marco Fraccalvieri, Stefano Bacci, Francesca Rossi
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1302039
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