Pediatric allergic disease is a significant health concern worldwide, and the prevalence of childhood eczema, asthma, allergic rhinitis, and food allergy continues to increase. Evidence to support specific interventions for the prevention of eczema, asthma, and allergic rhinitis is limited, and no consensus on prevention strategies has been reached. Randomized controlled trials investigating the prevention of food allergy via oral tolerance induction and the early introduction of allergenic foods have been successful in reducing peanut and egg allergy prevalence. Infant weaning guidelines in the United Sates were recently amended to actively encourage the introduction of peanut for prevention of peanut allergy.
Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance / Logan, K., Du Toit, G., Giovannini, M., Turcanu, V., Lack, G.. - In: ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY. - ISSN 1081-0706. - ELETTRONICO. - 36:(2020), pp. 511-528. [10.1146/annurev-cellbio-100818-125346]
Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance
Giovannini, Mattia;
2020
Abstract
Pediatric allergic disease is a significant health concern worldwide, and the prevalence of childhood eczema, asthma, allergic rhinitis, and food allergy continues to increase. Evidence to support specific interventions for the prevention of eczema, asthma, and allergic rhinitis is limited, and no consensus on prevention strategies has been reached. Randomized controlled trials investigating the prevention of food allergy via oral tolerance induction and the early introduction of allergenic foods have been successful in reducing peanut and egg allergy prevalence. Infant weaning guidelines in the United Sates were recently amended to actively encourage the introduction of peanut for prevention of peanut allergy.
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