Background: Widespread vaccination and emergence of less aggressive SARS-CoV2 variants may have blunted the unfavourable outcomes of COVID-19 in nursing home (NH) residents. We analysed the course of COVID-19 epidemic in NHs of Florence, Italy, during the "Omicron era" and investigated the independent effect of SARS-CoV2 infection on death and hospitalization risk. Methods: Weekly SARS-CoV2 infection rates between November 2021 and March 2022 were calculated. Detailed clinical data were collected in a sample of NHs. Results: Among 2044 residents, 667 SARS-CoV2 cases were confirmed. SARS-CoV2 incidence sharply increased during the Omicron era. Mortality rates did not differ between SARS-CoV2-positive (6.9%) and SARS-CoV2-negative residents (7.3%, p = 0.71). Chronic obstructive pulmonary disease and poor functional status, but not SARS-CoV2 infection independently predicted death and hospitalization. Conclusions: Despite that SARS-CoV2 incidence increased during the Omicron era, SARS-CoV2 infection was not a significant predictor of hospitalization and death in the NH setting.

Impact of SARS-CoV2 infection on mortality and hospitalization in nursing home residents during the "Omicron era" / Bulgaresi, Matteo; Rivasi, Giulia; Tarantini, Francesca; Espinoza Tofalos, Sofia; Del Re, Lorenzo Maria; Salucci, Caterina; Turrin, Giada; Barucci, Riccardo; Bandinelli, Chiara; Fattorini, Letizia; Borchi, Daniele; Betti, Marta; Checchi, Saverio; Baggiani, Lorenzo; Collini, Francesca; Lorini, Chiara; Bonaccorsi, Guglielmo; Ungar, Andrea; Mossello, Enrico; Benvenuti, Enrico. - In: AGING CLINICAL AND EXPERIMENTAL RESEARCH. - ISSN 1720-8319. - ELETTRONICO. - --:(2023), pp. 0-0. [10.1007/s40520-023-02415-w]

Impact of SARS-CoV2 infection on mortality and hospitalization in nursing home residents during the "Omicron era"

Bulgaresi, Matteo;Rivasi, Giulia
;
Tarantini, Francesca;Espinoza Tofalos, Sofia;Del Re, Lorenzo Maria;Salucci, Caterina;Turrin, Giada;Barucci, Riccardo;Bandinelli, Chiara;Fattorini, Letizia;Borchi, Daniele;Betti, Marta;Checchi, Saverio;Baggiani, Lorenzo;Collini, Francesca;Lorini, Chiara;Bonaccorsi, Guglielmo;Ungar, Andrea;Mossello, Enrico;Benvenuti, Enrico
2023

Abstract

Background: Widespread vaccination and emergence of less aggressive SARS-CoV2 variants may have blunted the unfavourable outcomes of COVID-19 in nursing home (NH) residents. We analysed the course of COVID-19 epidemic in NHs of Florence, Italy, during the "Omicron era" and investigated the independent effect of SARS-CoV2 infection on death and hospitalization risk. Methods: Weekly SARS-CoV2 infection rates between November 2021 and March 2022 were calculated. Detailed clinical data were collected in a sample of NHs. Results: Among 2044 residents, 667 SARS-CoV2 cases were confirmed. SARS-CoV2 incidence sharply increased during the Omicron era. Mortality rates did not differ between SARS-CoV2-positive (6.9%) and SARS-CoV2-negative residents (7.3%, p = 0.71). Chronic obstructive pulmonary disease and poor functional status, but not SARS-CoV2 infection independently predicted death and hospitalization. Conclusions: Despite that SARS-CoV2 incidence increased during the Omicron era, SARS-CoV2 infection was not a significant predictor of hospitalization and death in the NH setting.
2023
--
0
0
Goal 3: Good health and well-being
Bulgaresi, Matteo; Rivasi, Giulia; Tarantini, Francesca; Espinoza Tofalos, Sofia; Del Re, Lorenzo Maria; Salucci, Caterina; Turrin, Giada; Barucci, Riccardo; Bandinelli, Chiara; Fattorini, Letizia; Borchi, Daniele; Betti, Marta; Checchi, Saverio; Baggiani, Lorenzo; Collini, Francesca; Lorini, Chiara; Bonaccorsi, Guglielmo; Ungar, Andrea; Mossello, Enrico; Benvenuti, Enrico
File in questo prodotto:
File Dimensione Formato  
Manuscript for short communication 04.2023.pdf

Accesso chiuso

Tipologia: Preprint (Submitted version)
Licenza: Tutti i diritti riservati
Dimensione 800.58 kB
Formato Adobe PDF
800.58 kB Adobe PDF   Richiedi una copia

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1308690
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact