The first pathotype responds poorly to conventional synthetic DMARD therapy, while it has a better response to anti-IL-6; the second responds to anti-TNF; and the pauci-immune has a poor response to treatments, although it is characterized by less activity and minimal radiographic progression [2], invariably correlated with painful joint counts and significantly higher patient-reported pain, fatigue and general health outcomes [3].
Pauci-immune synovitis in other inflammatory arthritides: it's not just a subtype of rheumatoid arthritis that is unresponsive to treatment / Galluccio, Felice; Capassoni, Marco; Ketabchi, Sheyda; Guiducci, Serena. - In: RHEUMATOLOGY. - ISSN 1462-0332. - ELETTRONICO. - 61:(2022), pp. 1728-1729. [10.1093/rheumatology/keab899]
Pauci-immune synovitis in other inflammatory arthritides: it's not just a subtype of rheumatoid arthritis that is unresponsive to treatment
Galluccio, Felice;Capassoni, Marco;Ketabchi, Sheyda;Guiducci, Serena
2022
Abstract
The first pathotype responds poorly to conventional synthetic DMARD therapy, while it has a better response to anti-IL-6; the second responds to anti-TNF; and the pauci-immune has a poor response to treatments, although it is characterized by less activity and minimal radiographic progression [2], invariably correlated with painful joint counts and significantly higher patient-reported pain, fatigue and general health outcomes [3].
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