Background: Incidentally diagnosed adrenal masses represent an entity that can result in either long term follow-up, surgical excision, or both. Understanding when and which adrenal masses are ultimately excised surgically is not well understood. We sought to understand the ultimate fate of these incidentalomas using a large population-based dataset. Methods: The primary outcome of the study was determining the trend in adoption of surveillance vs. surgical excision according to socio-demographic, economic, and pathologic indices, and also provider specialty. Secondary outcomes were the assessment of perioperative complications, operative time, surgical approach, hospital stay, and provider specialty (general surgery vs. urology) among the cohort that underwent excision. Results: Out of a total of N.=91,560 adrenal masses, ultimately N.=3375 (3.83%) of these underwent surgical excision. In the surgical excision cohort, the incidence of aldosteronoma, functional adenoma/Cushing's disease, and adrenocortical carcinoma was higher than in the surveillance cohort. Those patients who were older, female, and with higher Charlson Comorbidity indexes (CCI) were less likely to undergo surgical resection. Factors that predicted for an increased probability of resection included obtaining more CT/MRI scans as well as general surgeons as primary physician providers. Over the study period, the vast majority of surgeries were performed by surgeons other than urologists (12.9%) and open and laparoscopic approaches dominated, with the robotic-assisted approach accounting for a minority of the surgical cases (23.9%). The minimally invasive surgery (MIS) approach independently predicted for both lower rates of complications and shorter hospital stay. Conclusions: In the US, adrenal incidentalomas are more likely to undergo surveillance rather than surgical resection. In our study, surgery is mainly offered for functional or malignant disease and the receipt of surgery can vary by physician specialty. A MIS approach independently predicted for both lower rates of complications and shorter hospital stay.

Management of the incidental adrenal mass, continued surveillance versus surgical excision: analysis of US claims data on contemporary socio-demographic predictors and perioperative outcomes / Del Giudice, Francesco; Kim, Wansuk; Li, Shufeng; DE Berardinis, Ettore; Sciarra, Alessandro; Salciccia, Stefano; Ferro, Matteo; Autorino, Riccardo; Pandolfo, Savio D; Crocetto, Felice; Galfano, Antonio; Dell'oglio, Paolo; Cacciamani, Giovanni E; Pradere, Benjamin; Laukhtina, Ekaterina; D'Andrea, David; Belladelli, Federico; Krajewski, Wojciech; Mari, Andrea; Minervini, Andrea; Gallioli, Andrea; Amparore, Daniele; Checcucci, Enrico; Fiori, Cristian; Porpiglia, Francesco; Morgantini, Luca; Crivellaro, Simone; Chung, Benjamin I. - In: MINERVA UROLOGY AND NEPHROLOGY. - ISSN 2724-6051. - ELETTRONICO. - 75:(2023), pp. 73-84. [10.23736/S2724-6051.22.05073-X]

Management of the incidental adrenal mass, continued surveillance versus surgical excision: analysis of US claims data on contemporary socio-demographic predictors and perioperative outcomes

Mari, Andrea;Minervini, Andrea;
2023

Abstract

Background: Incidentally diagnosed adrenal masses represent an entity that can result in either long term follow-up, surgical excision, or both. Understanding when and which adrenal masses are ultimately excised surgically is not well understood. We sought to understand the ultimate fate of these incidentalomas using a large population-based dataset. Methods: The primary outcome of the study was determining the trend in adoption of surveillance vs. surgical excision according to socio-demographic, economic, and pathologic indices, and also provider specialty. Secondary outcomes were the assessment of perioperative complications, operative time, surgical approach, hospital stay, and provider specialty (general surgery vs. urology) among the cohort that underwent excision. Results: Out of a total of N.=91,560 adrenal masses, ultimately N.=3375 (3.83%) of these underwent surgical excision. In the surgical excision cohort, the incidence of aldosteronoma, functional adenoma/Cushing's disease, and adrenocortical carcinoma was higher than in the surveillance cohort. Those patients who were older, female, and with higher Charlson Comorbidity indexes (CCI) were less likely to undergo surgical resection. Factors that predicted for an increased probability of resection included obtaining more CT/MRI scans as well as general surgeons as primary physician providers. Over the study period, the vast majority of surgeries were performed by surgeons other than urologists (12.9%) and open and laparoscopic approaches dominated, with the robotic-assisted approach accounting for a minority of the surgical cases (23.9%). The minimally invasive surgery (MIS) approach independently predicted for both lower rates of complications and shorter hospital stay. Conclusions: In the US, adrenal incidentalomas are more likely to undergo surveillance rather than surgical resection. In our study, surgery is mainly offered for functional or malignant disease and the receipt of surgery can vary by physician specialty. A MIS approach independently predicted for both lower rates of complications and shorter hospital stay.
2023
75
73
84
Del Giudice, Francesco; Kim, Wansuk; Li, Shufeng; DE Berardinis, Ettore; Sciarra, Alessandro; Salciccia, Stefano; Ferro, Matteo; Autorino, Riccardo; Pandolfo, Savio D; Crocetto, Felice; Galfano, Antonio; Dell'oglio, Paolo; Cacciamani, Giovanni E; Pradere, Benjamin; Laukhtina, Ekaterina; D'Andrea, David; Belladelli, Federico; Krajewski, Wojciech; Mari, Andrea; Minervini, Andrea; Gallioli, Andrea; Amparore, Daniele; Checcucci, Enrico; Fiori, Cristian; Porpiglia, Francesco; Morgantini, Luca; Crivellaro, Simone; Chung, Benjamin I
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1309283
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