Cancer immunosurveillance generally relies on adaptive immune programs executed by CD8(+)T cells. Our findings demonstrate that CD8(+)T cells fail to control early oncogenesis in a mouse model of luminal B breast cancer and suggest that natural killer (NK) cells may instead play a predominant role in this setting.
NK cells beat T cells at early breast cancer control / Buque, Aitziber; Bloy, Norma; Petroni, Giulia; Kroemer, Guido; Galluzzi, Lorenzo. - In: ONCOIMMUNOLOGY. - ISSN 2162-4011. - ELETTRONICO. - 9:(2020), pp. 0-0. [10.1080/2162402X.2020.1806010]
NK cells beat T cells at early breast cancer control
Petroni, Giulia;Galluzzi, Lorenzo
2020
Abstract
Cancer immunosurveillance generally relies on adaptive immune programs executed by CD8(+)T cells. Our findings demonstrate that CD8(+)T cells fail to control early oncogenesis in a mouse model of luminal B breast cancer and suggest that natural killer (NK) cells may instead play a predominant role in this setting.
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