Whether cell death caused by T lymphocytes and natural killer (NK) cells would be immunogenic per se has been a matter of intense debate. Two back-to-back papers from the Melero's and Pardo's groups have now resolved this conundrum, demonstrating that T and NK cell-mediated cytotoxicity represents indeed a bona fide variant of immunogenic cell death.
Immunogenicity of cell death driven by immune effectors / Lorenzo Galluzzi; Giulia Petroni; Guido Kroemer. - In: JOURNAL FOR IMMUNOTHERAPY OF CANCER. - ISSN 2051-1426. - ELETTRONICO. - 8:(2020), pp. 0-0. [10.1136/jitc-2020-000802]
Immunogenicity of cell death driven by immune effectors
Lorenzo Galluzzi;Giulia Petroni;
2020
Abstract
Whether cell death caused by T lymphocytes and natural killer (NK) cells would be immunogenic per se has been a matter of intense debate. Two back-to-back papers from the Melero's and Pardo's groups have now resolved this conundrum, demonstrating that T and NK cell-mediated cytotoxicity represents indeed a bona fide variant of immunogenic cell death.File in questo prodotto:
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