Hypertension plays an important role in the development of heart damage. In this paper we analyze the topological properties of the capillary network in control and Spontaneously Hypertensive Rat (SHR) heart tissue. Sectional images were segmented, using the Otsu method, and the Hausdorff dimension of the capillary network is evaluated using the box-counting algorithm. Preliminary results indicate SHR images present a slightly worse correspondence with the fractal model, a higher variability between different depths, and a lower fractal dimension.
Geometric alterations of capillary network in hypertension: preliminary results / Altamore V.; Giardini F.; Olianti C.; Costantini I.; Sacconi L.; Bocchi L.. - ELETTRONICO. - (2020), pp. 426-429. (Intervento presentato al convegno 7th National Congress of Bioengineering, GNB 2020 tenutosi a ita nel 2020).
Geometric alterations of capillary network in hypertension: preliminary results
Altamore V.;Giardini F.;Olianti C.;Costantini I.;Sacconi L.;Bocchi L.
2020
Abstract
Hypertension plays an important role in the development of heart damage. In this paper we analyze the topological properties of the capillary network in control and Spontaneously Hypertensive Rat (SHR) heart tissue. Sectional images were segmented, using the Otsu method, and the Hausdorff dimension of the capillary network is evaluated using the box-counting algorithm. Preliminary results indicate SHR images present a slightly worse correspondence with the fractal model, a higher variability between different depths, and a lower fractal dimension.
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