: The tumor ecosystem evolves with dynamic interactions between cancer and normal cells, and nutrients have emerged as new regulators of cancer hallmarks. Lactate has climbed the rankings as a multifunctional molecule orchestrating many aspects of the disease onset and progression. Here, we patchwork and discuss the main recent findings conferred during the EMBO workshop titled 'Lactate: Unconventional Roles of a Nutrient Along the Tumor Landscape.'
Unconventional roles of lactate along the tumor and immune landscape / Ippolito, Luigi; Sonveaux, Pierre; Chiarugi, Paola. - In: TRENDS IN ENDOCRINOLOGY AND METABOLISM. - ISSN 1879-3061. - ELETTRONICO. - 33:(2022), pp. 231-235. [10.1016/j.tem.2022.01.005]
Unconventional roles of lactate along the tumor and immune landscape
Ippolito, Luigi;Chiarugi, Paola
2022
Abstract
: The tumor ecosystem evolves with dynamic interactions between cancer and normal cells, and nutrients have emerged as new regulators of cancer hallmarks. Lactate has climbed the rankings as a multifunctional molecule orchestrating many aspects of the disease onset and progression. Here, we patchwork and discuss the main recent findings conferred during the EMBO workshop titled 'Lactate: Unconventional Roles of a Nutrient Along the Tumor Landscape.'
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