Skin gluten-related disorders: new and old cutaneous manifestations to be considered

Besides the well-known association between celiac disease (CD) and dermatitis herpetiformis, considered as the cutaneous specific manifestation of CD, many other muco-cutaneous disorders have been associated to gluten related disorders (GRD). In this review, we analyzed the main features of dermatological diseases with a proven association with GRD and those that improve after a gluten-free diet, focusing on the newly described cutaneous manifestations associated with non celiac gluten sensitivity (NCGS). Our main hypothesis is that a "cutaneous-gluten sensitivity," as specific cutaneous manifestation of NCGS, may exist and could represent a diagnostic marker of NCGS.