: Human respiratory syncytial virus (hRSV) is a significant cause of respiratory tract infections, particularly in young children and older adults. In this review, we aimed to comprehensively summarize what is known about the immune response to hRSV infection. We described the innate and adaptive immune components involved, including the recognition of RSV, the inflammatory response, the role of natural killer (NK) cells, antigen presentation, T cell response, and antibody production. Understanding the complex immune response to hRSV infection is crucial for developing effective interventions against this significant respiratory pathogen. Further investigations into the immune memory generated by hRSV infection and the development of strategies to enhance immune responses may hold promise for the prevention and management of hRSV-associated diseases.

Reshaping Our Knowledge: Advancements in Understanding the Immune Response to Human Respiratory Syncytial Virus / Attaianese, Federica; Guiducci, Sara; Trapani, Sandra; Barbati, Federica; Lodi, Lorenzo; Indolfi, Giuseppe; Azzari, Chiara; Ricci, Silvia. - In: PATHOGENS. - ISSN 2076-0817. - ELETTRONICO. - 12:(2023), pp. 0-0. [10.3390/pathogens12091118]

Reshaping Our Knowledge: Advancements in Understanding the Immune Response to Human Respiratory Syncytial Virus

Attaianese, Federica;Guiducci, Sara;Trapani, Sandra;Barbati, Federica;Lodi, Lorenzo;Indolfi, Giuseppe;Azzari, Chiara;Ricci, Silvia
2023

Abstract

: Human respiratory syncytial virus (hRSV) is a significant cause of respiratory tract infections, particularly in young children and older adults. In this review, we aimed to comprehensively summarize what is known about the immune response to hRSV infection. We described the innate and adaptive immune components involved, including the recognition of RSV, the inflammatory response, the role of natural killer (NK) cells, antigen presentation, T cell response, and antibody production. Understanding the complex immune response to hRSV infection is crucial for developing effective interventions against this significant respiratory pathogen. Further investigations into the immune memory generated by hRSV infection and the development of strategies to enhance immune responses may hold promise for the prevention and management of hRSV-associated diseases.
2023
12
0
0
Attaianese, Federica; Guiducci, Sara; Trapani, Sandra; Barbati, Federica; Lodi, Lorenzo; Indolfi, Giuseppe; Azzari, Chiara; Ricci, Silvia
File in questo prodotto:
File Dimensione Formato  
pathogens-12-01118.pdf

accesso aperto

Tipologia: Pdf editoriale (Version of record)
Licenza: Open Access
Dimensione 1.41 MB
Formato Adobe PDF
1.41 MB Adobe PDF

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1340896
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 3
social impact