In this poster, the results of the analysis of 46 pharmaceutical compounds in Supercritical Fluid Chromatography will be presented. Each compound had been analyzed with three different columns (DIOL, 2-PIC and DEA) and four modifiers (MeOH, MeOH/Water 98/2 V/V, ACN, ACN/Water 98/2 V/V). For the Methanol and Methanol/Water mixture conditions, experiments with an additive (Ammonium Formate) had also been performed. The analysis were performed in order to gather data for the development and optimization of SFC’s starting conditions and methods, which are often quite time-consuming tasks.
In silico modeling of retention times in Supercritical Fluid Chromatography (SFC) coupled with UV detector using QSRR approach / A. Tanzini, A. Dispas, H. Jambo, P.-Y. Sacré, N. Mennini, S. Orlandini, P. Hubert, C. Hubert. - ELETTRONICO. - (2024), pp. 23-23. (Intervento presentato al convegno CIRM Day 2024 tenutosi a Liége, Belgium nel 31 gennaio 2024).
In silico modeling of retention times in Supercritical Fluid Chromatography (SFC) coupled with UV detector using QSRR approach
N. Mennini;S. Orlandini;
2024
Abstract
In this poster, the results of the analysis of 46 pharmaceutical compounds in Supercritical Fluid Chromatography will be presented. Each compound had been analyzed with three different columns (DIOL, 2-PIC and DEA) and four modifiers (MeOH, MeOH/Water 98/2 V/V, ACN, ACN/Water 98/2 V/V). For the Methanol and Methanol/Water mixture conditions, experiments with an additive (Ammonium Formate) had also been performed. The analysis were performed in order to gather data for the development and optimization of SFC’s starting conditions and methods, which are often quite time-consuming tasks.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.