New chiral P,N-ferrocenyl imino-phosphine ligands have been synthesized and the absolute configuration of the stereocenters in each molecule has been determined by a single-crystal X-ray analysis of a common intermediate. PdII-allyl complexes of the new ligands have been isolated and tested as catalyst precursors in the asymmetric allylic alkylation of 1,3-diphenylprop-2-en-1-yl acetate with dimethyl malonate in different solvents. Quantitative yields and enantiomeric excesses as high as 80% have been obtained.
Novel chiral ferrocenyl-imino phosphine ligands and their use in palladium catalyzed allylic alkylations / Barbaro P; Bianchini C; Giambastiani G; Togni A. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 44:(2003), pp. 8279-8283. [10.1016/j.tetlet.2003.09.067]
Novel chiral ferrocenyl-imino phosphine ligands and their use in palladium catalyzed allylic alkylations
Giambastiani G;
2003
Abstract
New chiral P,N-ferrocenyl imino-phosphine ligands have been synthesized and the absolute configuration of the stereocenters in each molecule has been determined by a single-crystal X-ray analysis of a common intermediate. PdII-allyl complexes of the new ligands have been isolated and tested as catalyst precursors in the asymmetric allylic alkylation of 1,3-diphenylprop-2-en-1-yl acetate with dimethyl malonate in different solvents. Quantitative yields and enantiomeric excesses as high as 80% have been obtained.
| File | Dimensione | Formato | |
|---|---|---|---|
|
TL-2003-44-8279-8283.pdf
Accesso chiuso
Licenza:
Tutti i diritti riservati
Dimensione
127.19 kB
Formato
Adobe PDF
|
127.19 kB | Adobe PDF | Richiedi una copia |
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
