Editorial: Implications of the inflammatory role of skin dendritic cells for health, disease and forensic practice

Dendritic cells (DC) are specialized antigen presenting cells abundant in peripheral tissues such as skin. DC are found in the dermis and in the epidermis (i.e., Langerhans cells) in the skin and they are bone marrow derived. It’s known that skin DC migrate to the regional draining lymph node where they interact with naïve T cells to induce immune responses as acclaimed by the SALT concept proposed by J. Wayne Streilein in 1999. This editorial summarizes the contributions to the Frontiers Research Topic “Implications of the inflammatory role of skin dendritic cells for health, disease and forensic practice” appearing in Frontiers in Medicine section Translational Medicine. To better address and clarify the issues relating to this research field, the Research Topic consists of a part dedicated to reviews on general or specific arguments in another containing research articles on specific Research Topics.