Leukemia and lymphoma are the two most common forms of hematologic malignancy, and their etiology is largely unknown. Pathophysiological mechanisms suggest a possible association with air pollution, but little empirical evidence is available. We aimed to investigate the association between long-term residential exposure to outdoor air pollution and risk of leukemia and lymphoma. We pooled data from four cohorts from three Among the study population of 247,436 individuals, 760 leukemia and 1122 lymphoma cases were diagnosed consistent across the four cohorts and according to smoking status. Sex-specific analyses suggested that this and according to sex. Our results suggest that air pollution at the residence may be associated with adult leu
Long-term exposure to ambient air pollution and risk of leukemia and lymphoma in a pooled European cohort / Taj, Tahir; Chen, Jie; Rodopoulou, Sophia; Strak, Maciej; de Hoogh, Kees; Poulsen, Aslak Harbo; Andersen, Zorana J; Bellander, Tom; Brandt, Jørgen; Zitt, Emanuel; Fecht, Daniela; Forastiere, Francesco; Gulliver, John; Hertel, Ole; Hoffmann, Barbara; Hvidtfeldt, Ulla Arthur; Jørgensen, Jeanette T; Katsouyanni, Klea; Ketzel, Matthias; Lager, Anton; Leander, Karin; Liu, Shuo; Ljungman, Petter; Severi, Gianluca; Besson, Caroline; Magnusson, Patrik K E; Nagel, Gabriele; Pershagen, Göran; Peters, Annette; Rizzuto, Debora; Samoli, Evangelia; Sørensen, Mette; Stafoggia, Massimo; Tjønneland, Anne; Weinmayr, Gudrun; Wolf, Kathrin; Brunekreef, Bert; Hoek, Gerard; Raaschou-Nielsen, Ole. - In: ENVIRONMENTAL POLLUTION. - ISSN 1873-6424. - ELETTRONICO. - 343:(2024), pp. 123097.0-123097.0. [10.1016/j.envpol.2023.123097]
Long-term exposure to ambient air pollution and risk of leukemia and lymphoma in a pooled European cohort
Severi, Gianluca;
2024
Abstract
Leukemia and lymphoma are the two most common forms of hematologic malignancy, and their etiology is largely unknown. Pathophysiological mechanisms suggest a possible association with air pollution, but little empirical evidence is available. We aimed to investigate the association between long-term residential exposure to outdoor air pollution and risk of leukemia and lymphoma. We pooled data from four cohorts from three Among the study population of 247,436 individuals, 760 leukemia and 1122 lymphoma cases were diagnosed consistent across the four cohorts and according to smoking status. Sex-specific analyses suggested that this and according to sex. Our results suggest that air pollution at the residence may be associated with adult leu
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