Deep Learning-Based Workflow for Bone Segmentation and 3D Modeling in Cone-Beam CT Orthopedic Imaging

In this study, a deep learning-based workflow designed for the segmentation and 3D modeling of bones in cone beam computed tomography (CBCT) orthopedic imaging is presented. This workflow uses a convolutional neural network (CNN), specifically a U-Net architecture, to perform precise bone segmentation even in challenging anatomical regions such as limbs, joints, and extremities, where bone boundaries are less distinct and densities are highly variable. The effectiveness of the proposed workflow was evaluated by comparing the generated 3D models against those obtained through other segmentation methods, including SegNet, binary thresholding, and graph cut algorithms. The accuracy of these models was quantitatively assessed using the Jaccard index, the Dice coefficient, and the Hausdorff distance metrics. The results indicate that the U-Net-based segmentation consistently outperforms other techniques, producing more accurate and reliable 3D bone models. The user interface developed for this workflow facilitates intuitive visualization and manipulation of the 3D models, enhancing the usability and effectiveness of the segmentation process in both clinical and research settings. The findings suggest that the proposed deep learning-based workflow holds significant potential for improving the accuracy of bone segmentation and the quality of 3D models derived from CBCT scans, contributing to better diagnostic and pre-surgical planning outcomes in orthopedic practice.