Morphological Features of Full-Thickness Macular Holes Using Retromode Scanning Laser Ophthalmoscopy

BACKGROUND AND OBJECTIVE: Retromode scanning laser ophthalmoscopy (RM-SLO) is a new imaging modality displaying pseudo-3D retinal images. We assessed the correlation between the morphological features of full-thickness macular holes (FTMHs) when using spectral domain-optical coherence to-mography (SD-OCT) and when using RM-SLO. MATERIALS AND METHODS: This is a prospective ob-servational case series in which patients were exam-ined through SD-OCT and RM-SLO after informed consent was obtained. Intraclass correlation coeffi-cient (ICC) and Pearson correlation coefficient (PCC) were used to assess interobserver agreement and the correlation between the diameters measured with the two techniques. RESULTS: We enrolled 20 patients (20 eyes) with an average hole aperture size of 426 mu m (140-890 mu m) on SD-OCT and 56 pixels (19-102 pixels) on RM-SLO. ICC and PCC were 0.999 and 0.992, respec-tively. "Standard" and "double-ring" FTMH pat-terns were described on RM-SLO and related well with SD-OCT findings. CONCLUSIONS: RM-SLO is a reliable method for FTMH-diameter evaluation and identifies unique pseudo-3D morphological features consistent with their B-scan counterparts. [Ophthalmic Surg Lasers Imaging Retina 2022; 53:368-373.]