Chorioangiomas are benign angiomas arising from chorionic tissue and they are the most common non-trophoblastic tumors of the placenta, as they are observed in 1% of all pla-centas examined. Most chorioangiomas are small and asymptomatic, often undetected during a prenatal ultrasound, and their clinical significance is still unknown. Large chorio-angiomas, measuring more than 4-5 cm in diameter, can usually be detected prenatally by gray-scale or color Doppler sonography, and may be associated with maternal or fetal complications, such as preeclampsia, maternal mirror syndrome, preterm delivery, non-immune fetal hydrops, fetal growth restriction and fetal demise. We herein describe the clinical-pathological features of a monocentric series of 30 placental chorioangiomas and discuss their clinical-pathological features and possible molecular mechanisms underlying their development
A case series of chorioangiomas in placentas with clinical indication for histological examination / Eleonora Nardi, Angela Silvano, Francesca Castiglione, Erika Olivo, Isabella Abati, Daniela Massi, Viola Seravalli, Mariarosaria Di Tommaso. - In: PATHOLOGICA. - ISSN 1591-951X. - ELETTRONICO. - (2024), pp. 258-266.
A case series of chorioangiomas in placentas with clinical indication for histological examination
Eleonora Nardi
;Angela Silvano;Francesca Castiglione;Erika Olivo;Isabella Abati;Daniela Massi;Viola Seravalli;Mariarosaria Di Tommaso
2024
Abstract
Chorioangiomas are benign angiomas arising from chorionic tissue and they are the most common non-trophoblastic tumors of the placenta, as they are observed in 1% of all pla-centas examined. Most chorioangiomas are small and asymptomatic, often undetected during a prenatal ultrasound, and their clinical significance is still unknown. Large chorio-angiomas, measuring more than 4-5 cm in diameter, can usually be detected prenatally by gray-scale or color Doppler sonography, and may be associated with maternal or fetal complications, such as preeclampsia, maternal mirror syndrome, preterm delivery, non-immune fetal hydrops, fetal growth restriction and fetal demise. We herein describe the clinical-pathological features of a monocentric series of 30 placental chorioangiomas and discuss their clinical-pathological features and possible molecular mechanisms underlying their developmentFile | Dimensione | Formato | |
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