Introduction: In patients with obstructive hypertrophic cardiomyopathy (oHCM), the SEQUOIA-HCM trial demonstrated that aficamten, a next-in-class cardiac myosin inhibitor, improved exercise capacity, heart failure symptoms and hemodynamics compared with placebo. Aficamten’s impact on overall quality-of-life (QoL) in oHCM has not been reported.

Abstract 4140102: Changes in EQ-5D-5L with Aficamten in Obstructive Hypertrophic Cardiomyopathy (oHCM): the SEQUOIA-HCM Trial / Schulze, Christian; Abraham, Theodore; Barriales-Villa, Roberto; Claggett, Brian; Coats, Caroline; Garcia-Pavia, Pablo; Hagege, Albert; Januzzi, James; Kulac, Ian; Kwong, Raymond; maron, Martin; Masri, Ahmad; Nassif, Michael; Olivotto, Iacopo; Spertus, John; Veselka, Josef; Butzner, Michael; Heitner, Stephen; Jacoby, Daniel; Kupfer, Stuart; Malik, Fady; Meng, Lixin; Shreay, Sanatan; Wohltman, Amy; Maurer, Mathew. - In: CIRCULATION. - ISSN 0009-7322. - ELETTRONICO. - 150:(2024), pp. 0-0. [10.1161/circ.150.suppl_1.4140102]

Abstract 4140102: Changes in EQ-5D-5L with Aficamten in Obstructive Hypertrophic Cardiomyopathy (oHCM): the SEQUOIA-HCM Trial

Olivotto, Iacopo;
2024

Abstract

Introduction: In patients with obstructive hypertrophic cardiomyopathy (oHCM), the SEQUOIA-HCM trial demonstrated that aficamten, a next-in-class cardiac myosin inhibitor, improved exercise capacity, heart failure symptoms and hemodynamics compared with placebo. Aficamten’s impact on overall quality-of-life (QoL) in oHCM has not been reported.
2024
Schulze, Christian; Abraham, Theodore; Barriales-Villa, Roberto; Claggett, Brian; Coats, Caroline; Garcia-Pavia, Pablo; Hagege, Albert; Januzzi, James...espandi
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1402064
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