In the last two decades, the study of ion channels and transporters in cancer has been exponentially growing. Many of these proteins have been implicated in several cellular processes as cancer cell proliferation, migration, invasion, tumor vascularization and metastasis, revealing them as key factors in cancer biology. Such view is in line with the association of cancer with the term oncochannelopathy. We are happy to present a Research Topic of articles in Frontiers in Pharmacology highlighting ion channels and membrane transporters as new potential targets for cancer treatment. The total Research Topic brings together unique contributions from original research to review articles covering the dysregulation of a variety of channels and transporters in multiple cancers, emphasizing the importance of these proteins for diagnostic, prognostic and therapeutic purposes.
Editorial: Novel therapeutic approach in cancer: the role of ion channels and transporters / Altamura, Concetta; Lastraioli, Elena. - In: FRONTIERS IN PHARMACOLOGY. - ISSN 1663-9812. - ELETTRONICO. - 15:(2024), pp. 1422127.0-1422127.0. [10.3389/fphar.2024.1422127]
Editorial: Novel therapeutic approach in cancer: the role of ion channels and transporters
Lastraioli, Elena
2024
Abstract
In the last two decades, the study of ion channels and transporters in cancer has been exponentially growing. Many of these proteins have been implicated in several cellular processes as cancer cell proliferation, migration, invasion, tumor vascularization and metastasis, revealing them as key factors in cancer biology. Such view is in line with the association of cancer with the term oncochannelopathy. We are happy to present a Research Topic of articles in Frontiers in Pharmacology highlighting ion channels and membrane transporters as new potential targets for cancer treatment. The total Research Topic brings together unique contributions from original research to review articles covering the dysregulation of a variety of channels and transporters in multiple cancers, emphasizing the importance of these proteins for diagnostic, prognostic and therapeutic purposes.File | Dimensione | Formato | |
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