Formoterol is included in the World Anti-Doping Agency list of prohibited substances and methods. In 2012 a threshold of 30 ng/mL was established to differentiate between the prohibited oral and the permitted inhalatory administration. In this study the formoterol kinetics of degradation in urine and its metabolic profile after inhalation of different doses of medicaments containing formoterol fumarate bihydrate were investigated by a rapid LC-ESI-MS/MS procedure
A simple and rapid procedure for the determination of the urinary concentration of formoterol by LC-MS/MS / M. Mazzarino; I. Fiacco; S. Turi; BOTRE', Francesco. - STAMPA. - 20:(2012), pp. 139-143. (Intervento presentato al convegno MANFRED DONIKE WORKSHOP tenutosi a COLONIA nel FEBBRAIO-MARZO 2012).
A simple and rapid procedure for the determination of the urinary concentration of formoterol by LC-MS/MS
BOTRE', Francesco
2012
Abstract
Formoterol is included in the World Anti-Doping Agency list of prohibited substances and methods. In 2012 a threshold of 30 ng/mL was established to differentiate between the prohibited oral and the permitted inhalatory administration. In this study the formoterol kinetics of degradation in urine and its metabolic profile after inhalation of different doses of medicaments containing formoterol fumarate bihydrate were investigated by a rapid LC-ESI-MS/MS procedure
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