Pulsed Field Ablation (PFA) is a technique to achieve pulmonary vein isolation, alternative to the traditional thermal ablation procedures. Instead of delivering or subtracting heat, PFA uses rapid pulses of a high intensity electric field, inducing cells electroporation. PFA is usually claimed not to influence the temperature in the surroundings of the ablation site. Nevertheless, in some case a non-negligible increase of the patient’s luminal esophageal temperature has been observed. Here we set up a mathematical model to provide a theoretical basis to the latter observation, considering a worst case scenario.

Heat delivery accompanying pulsed field ablation / Farina, Angiolo; Fasano, Antonio; Grimaldi, Massimo; Rosso, Fabio. - In: JOURNAL OF THEORETICAL BIOLOGY. - ISSN 0022-5193. - ELETTRONICO. - 610:(2025), pp. 0-0. [10.1016/j.jtbi.2025.112145]

Heat delivery accompanying pulsed field ablation

Farina, Angiolo
;
Fasano, Antonio;Grimaldi, Massimo;Rosso, Fabio
2025

Abstract

Pulsed Field Ablation (PFA) is a technique to achieve pulmonary vein isolation, alternative to the traditional thermal ablation procedures. Instead of delivering or subtracting heat, PFA uses rapid pulses of a high intensity electric field, inducing cells electroporation. PFA is usually claimed not to influence the temperature in the surroundings of the ablation site. Nevertheless, in some case a non-negligible increase of the patient’s luminal esophageal temperature has been observed. Here we set up a mathematical model to provide a theoretical basis to the latter observation, considering a worst case scenario.
2025
610
0
0
Farina, Angiolo; Fasano, Antonio; Grimaldi, Massimo; Rosso, Fabio
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1424652
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