Pulsed Field Ablation (PFA) is a technique to achieve pulmonary vein isolation, alternative to the traditional thermal ablation procedures. Instead of delivering or subtracting heat, PFA uses rapid pulses of a high intensity electric field, inducing cells electroporation. PFA is usually claimed not to influence the temperature in the surroundings of the ablation site. Nevertheless, in some case a non-negligible increase of the patient’s luminal esophageal temperature has been observed. Here we set up a mathematical model to provide a theoretical basis to the latter observation, considering a worst case scenario.
Heat delivery accompanying pulsed field ablation / Farina, Angiolo; Fasano, Antonio; Grimaldi, Massimo; Rosso, Fabio. - In: JOURNAL OF THEORETICAL BIOLOGY. - ISSN 0022-5193. - ELETTRONICO. - 610:(2025), pp. 0-0. [10.1016/j.jtbi.2025.112145]
Heat delivery accompanying pulsed field ablation
Farina, Angiolo
;Fasano, Antonio;Grimaldi, Massimo;Rosso, Fabio
2025
Abstract
Pulsed Field Ablation (PFA) is a technique to achieve pulmonary vein isolation, alternative to the traditional thermal ablation procedures. Instead of delivering or subtracting heat, PFA uses rapid pulses of a high intensity electric field, inducing cells electroporation. PFA is usually claimed not to influence the temperature in the surroundings of the ablation site. Nevertheless, in some case a non-negligible increase of the patient’s luminal esophageal temperature has been observed. Here we set up a mathematical model to provide a theoretical basis to the latter observation, considering a worst case scenario.| File | Dimensione | Formato | |
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