The Higher Order Structure (HOS) of multispecific biologics and conventional monoclonal antibodies can be inspected by mapping the fingerprint "left" on the target using solid-state NMR (SSNMR).
NMR reveals the binding mode of three different full-length clinically approved monoclonal antibodies for the same target / Linda Cerofolini, Rebecca Calamandrei, Francesca Sacco, Bianca Susini, Sara Callozzo, Pasquale Russomanno, Enrico Ravera, Fabio Baroni, Marco Fragai. - ELETTRONICO. - (2025), pp. 1-1. (Intervento presentato al convegno Hands-on Workshop Spring 2025 Panacea).
NMR reveals the binding mode of three different full-length clinically approved monoclonal antibodies for the same target
Linda Cerofolini;Rebecca Calamandrei;Francesca Sacco;Bianca Susini;Sara Callozzo;Pasquale Russomanno;Enrico Ravera;Marco Fragai
2025
Abstract
The Higher Order Structure (HOS) of multispecific biologics and conventional monoclonal antibodies can be inspected by mapping the fingerprint "left" on the target using solid-state NMR (SSNMR).
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