MiniADAM: from a lung-equivalent compressible material to a miniaturized breathing phantom for theranostic applications

The field of radiation therapy is continuously advancing in targeting malignant tissues. However, radiotherapy treatment for lesions in moving organs, such as the lungs, remains a significant challenge. Furthermore, the development of phantoms capable of accurately simulating the architecture and morphological features of healthy and diseased lungs is still limited. This study, evolved in the frame of PRIN 2022 ALPHA project, aims to develop a multi-purpose lung phantom prototype that replicates both the respiratory dynamics and the morphological features observed in clinical radiological imaging (CT and MRI) of lung parenchyma.