2025 ICM: Use of Antibiotic Impregnated Polymethyl Methacrylate Cement

Guerra-Farfán, Ernesto; Akkaya, Mustafa; Jarusriwanna, Atthakorn; Amri, Khalil; Bayam, Levent; Busato, Thiago Sampaio; Buttacavoli, Frank; Chai, Wei; Chareancholvanich, Keerati; Chen, Cheng-Fong; Costantini, Julian; Delanois, Ronald E.; Dunbar, Michael; Ekhtiari, Seper; Gavrankapetanović, Ismet; Gonçalves, Sérgio; Grenho, André; Innocenti, Matteo; Jenny, Jean-Yves; Klaber, Ianiv; Lazarinis, Stergios; Levine, Brett R.; Masters, Elysia; Sanz-Ruiz, Pablo; Unnanuntana, Aasis

doi:10.1016/j.arth.2025.10.073

2025 ICM: Use of Antibiotic-Impregnated Polymethyl Methacrylate Cement Does the use of antibiotic-impregnated polymethyl methacrylate cement reduce the incidence of infection in patients undergoing primary joint arthroplasty? Response/Recommendation: The evidence among lower-level comparative studies is mixed, with some studies suggesting that antibiotic-impregnated cement reduces the risk of infection in patients undergoing primary joint arthroplasty. However, pooling of the available Level 1 evidence, as well as pooled registry data, does not support a reduction in infection risk in primary total joint arthroplasty.

2025 ICM: Use of Antibiotic Impregnated Polymethyl Methacrylate Cement / Guerra-Farfán, E., Akkaya, M., Jarusriwanna, A., Amri, K., Bayam, L., Busato, T.S., Buttacavoli, F., Chai, W., Chareancholvanich, K., Chen, C., Costantini, J., Delanois, R.E., Dunbar, M., Ekhtiari, S., Gavrankapetanović, I., Gonçalves, S., Grenho, A., Innocenti, M., Jenny, J., Klaber, I., et al.. - In: THE JOURNAL OF ARTHROPLASTY. - ISSN 0883-5403. - ELETTRONICO. - (2025), pp. 0-0. [10.1016/j.arth.2025.10.073]