We develop a new theoretical framework for birods—a model for 2-braids and intertwined molecules such as DNA—grounded in continuum mechanics and built upon invariance principles. We represent birods as Cosserat curves enriched by additional phase fields. We look at large strain setting and consider virtually varying reference configurations as a tool for describing structural mutations like those induced by the helicase in DNA. Actions are associated with each independent mechanism that changes the birod shape. We deduce pertinent balance equations by requiring objectivity to the power of external actions relatively to virtually varying reference configurations and a power of disarrangement. We do not postulate the expression of the inner power of actions, which is instead derived. In other words, we deliberately avoid the principle of virtual power, that is, we do not postulate a weak form of the balance equations in dynamical setting. Then, by looking at loops, we find closed form expressions of the energy changes due to variations of the loop writhe number. The results pertain to a class of mechanisms that includes DNA supercoiling.

Topological changes in birods and loops / Paolo Maria Mariano; Domenico Mucci. - In: JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS. - ISSN 0022-5096. - STAMPA. - 206:(2026), pp. 106414.1-106414.19. [10.1016/j.jmps.2025.106414]

Topological changes in birods and loops

Paolo Maria Mariano
;
2026

Abstract

We develop a new theoretical framework for birods—a model for 2-braids and intertwined molecules such as DNA—grounded in continuum mechanics and built upon invariance principles. We represent birods as Cosserat curves enriched by additional phase fields. We look at large strain setting and consider virtually varying reference configurations as a tool for describing structural mutations like those induced by the helicase in DNA. Actions are associated with each independent mechanism that changes the birod shape. We deduce pertinent balance equations by requiring objectivity to the power of external actions relatively to virtually varying reference configurations and a power of disarrangement. We do not postulate the expression of the inner power of actions, which is instead derived. In other words, we deliberately avoid the principle of virtual power, that is, we do not postulate a weak form of the balance equations in dynamical setting. Then, by looking at loops, we find closed form expressions of the energy changes due to variations of the loop writhe number. The results pertain to a class of mechanisms that includes DNA supercoiling.
2026
206
1
19
Goal 4: Quality education
Goal 9: Industry, Innovation, and Infrastructure
Goal 10: Reduced inequalities
Paolo Maria Mariano; Domenico Mucci
File in questo prodotto:
File Dimensione Formato  
J118.pdf

accesso aperto

Tipologia: Pdf editoriale (Version of record)
Licenza: Open Access
Dimensione 1.53 MB
Formato Adobe PDF
1.53 MB Adobe PDF

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1439421
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact