Rejuvenation of intestinal microbiota via microbiota transfer in aged mice: effects on local expression of proteins and function.

We have previously shown that microbiota transfer from aged donors into young recipients triggered a series of event leading to changes at systemic level, including the nervous central system1. Here we sought to evaluate the e.ects of the rejuvenation of intestinal microbiota via microbial transfer from young donors into aged recipient mice on the intestinal expression of proteins and function.