In this work we investigate the effectiveness of a water-soluble agent, the 2,2'- thiodiethanol (TDE) to clear mouse and human brain. TDE is suitable with two-photon fluorescence microscopy and in combination with CLARITY with light sheet microscopy.
A multi modal clearing method for brain imaging / Costantini I.; Mascaro A.L.A.; Di Giovanna A.P.; Silvestri L.; Mullenbroich M.C.; Sacconi L.; Pavone F.S.. - ELETTRONICO. - (2015), pp. 0-0. ( Optics and the Brain, BRAIN 2015 Pinnacle Vancouver Harbourfront Hotel, can 2015) [10.1364/brain.2015.brm3b.2].
A multi modal clearing method for brain imaging
Costantini I.;Di Giovanna A. P.;Silvestri L.;Mullenbroich M. C.;Sacconi L.;Pavone F. S.
2015
Abstract
In this work we investigate the effectiveness of a water-soluble agent, the 2,2'- thiodiethanol (TDE) to clear mouse and human brain. TDE is suitable with two-photon fluorescence microscopy and in combination with CLARITY with light sheet microscopy.
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