Excitation spectra overlap between fluorescence indicators and optogenetic tools limits the development of an all-optical system for neural circuits interrogation. Here we describe how we solved the puzzle by combining red-shifted GECI with Channelrhodopsin 2.
All-optical simultaneous stimulation and readout of motor cortex activity in Awake Mice / Resta F.; Conti E.; Montagni E.; Sacconi L.; Allegra Mascaro A.L.; Pavone F.S.. - ELETTRONICO. - 2018:(2018), pp. 0-0. ( Clinical and Translational Biophotonics, TRANSLATIONAL 2018 usa 2018) [10.1364/TRANSLATIONAL.2018.JTu3A.47].
All-optical simultaneous stimulation and readout of motor cortex activity in Awake Mice
Resta F.;Conti E.;Montagni E.;Sacconi L.;Allegra Mascaro A. L.;Pavone F. S.
2018
Abstract
Excitation spectra overlap between fluorescence indicators and optogenetic tools limits the development of an all-optical system for neural circuits interrogation. Here we describe how we solved the puzzle by combining red-shifted GECI with Channelrhodopsin 2.
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