Combined Use of Relabotulinum Toxin A and NASHA Gel Skinbooster for Rejuvenation of the Upper Third of the Face

Background: Aging of the upper third of the face is characterized by dynamic forehead wrinkles and volume loss in the temporal region, resulting in a fatigued and aged appearance. Addressing both muscle hyperactivity and soft tissue atrophy is essential for effective rejuvenation. Objective: To evaluate a combined injectable treatment protocol using Relabotulinum Toxin A for frontalis muscle modulation and NASHA™-based gel skinbooster for temporal skin quality enhancement. Methods: Patients received intramuscular injections of Relabotulinum Toxin A targeting the frontalis muscle, followed by three monthly sessions of NASHA gel skinbooster injected subcutaneously into the temporal region using a blunt cannula technique. Dosages and injection points were individualized based on detailed anatomical and functional assessments. Results: Preliminary clinical evaluations indicate that the protocol is minimally invasive and well-tolerated, producing progressive aesthetic improvements lasting beyond six months. Patients reported enhanced skin tone, elasticity, hydration, and a natural-looking lift of the eyebrow tail. Improvements in psychological well-being and patient satisfaction were also observed. Conclusion: This combined neuromodulation and skin quality improvement approach provides a comprehensive and synergistic strategy for upper facial rejuvenation. The ready-to-use liquid formulation of Relabotulinum Toxin A allows for precise application, rapid onset of results within 24-48 hours, and sustained improvement of forehead dynamic wrinkles for up to six months. The collagen-stimulating properties of NASHA gel deliver natural, long-lasting enhancement of the temporal region, contributing to high levels of patient satisfaction.  .