In the adult nervous system, different neuronal classes show different regenerative behavior. Although previous studies demonstrated that olivocerebellar fibers are capable of axonal regeneration in a suitable environment as a response to injury, we have hitherto no details about the real dynamics of fiber regeneration. We set up a model of singularly axotomized climbing fibers (CF) to investigate their reparative properties in the adult central nervous system (CNS) in vivo. Here we describe the approach followed to characterize the reactive plasticity after injury © 2013 OSA-SPIE.
In vivo two-photon imaging of climbing fibers plasticity after laser axotomy / Allegra Mascaro A.L.; Cesare P.; Sacconi L.; Grasselli G.; Mandolesi G.; Maco B.; Knott G.W.; De Paola V.; Strata P.; Pavone F.S.. - ELETTRONICO. - (2013), pp. 0-0. ( European Conference on Biomedical Optics, ECBO 2013 Munich, deu 2013).
In vivo two-photon imaging of climbing fibers plasticity after laser axotomy
Allegra Mascaro A. L.;Sacconi L.;Pavone F. S.
2013
Abstract
In the adult nervous system, different neuronal classes show different regenerative behavior. Although previous studies demonstrated that olivocerebellar fibers are capable of axonal regeneration in a suitable environment as a response to injury, we have hitherto no details about the real dynamics of fiber regeneration. We set up a model of singularly axotomized climbing fibers (CF) to investigate their reparative properties in the adult central nervous system (CNS) in vivo. Here we describe the approach followed to characterize the reactive plasticity after injury © 2013 OSA-SPIE.
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