Research project within the FC-RELAX : The anticipated results of this research are: 1) Successful formation and comprehensive study of Gd(III) and Eu(III) complexes using DOTP, HP-DO3P and HP2-DO2P ligands, enabling a deeper understanding of their structural and functional properties. 2) Identification and elucidation of the kinetic parameters governing the proton exchange between Gd(III) and Eu(III) complexes and the solvent water protons. 3) Revelation of in vivo catalysts facilitating the proton exchange between Gd(III) complexes and bulk solvent molecules. 4) In-depth studies of the thermodynamic, kinetic, and structural features necessary for the effective in vivo utilization of Gd(III) and Eu(III) complexes as MRI contrast agents, potentially paving the way for the development of novel MRI contrast agent with improved efficiency

Personal Introduction: My Academic Journey, Passion Areas, and Research Goals within the FC-RELAX Project No. 9 titled "Pure proton-exchange based relaxation agent for MRI applications" Author: Madalina Ranga / Madalina Ranga. - ELETTRONICO. - (2024), pp. 1-2. ( FC-RELAX Event Lisbon 15-17 April 2024).

Personal Introduction: My Academic Journey, Passion Areas, and Research Goals within the FC-RELAX Project No. 9 titled "Pure proton-exchange based relaxation agent for MRI applications" Author: Madalina Ranga

Madalina Ranga
2024

Abstract

Research project within the FC-RELAX : The anticipated results of this research are: 1) Successful formation and comprehensive study of Gd(III) and Eu(III) complexes using DOTP, HP-DO3P and HP2-DO2P ligands, enabling a deeper understanding of their structural and functional properties. 2) Identification and elucidation of the kinetic parameters governing the proton exchange between Gd(III) and Eu(III) complexes and the solvent water protons. 3) Revelation of in vivo catalysts facilitating the proton exchange between Gd(III) complexes and bulk solvent molecules. 4) In-depth studies of the thermodynamic, kinetic, and structural features necessary for the effective in vivo utilization of Gd(III) and Eu(III) complexes as MRI contrast agents, potentially paving the way for the development of novel MRI contrast agent with improved efficiency
2024
Mid-term Meeting of NMR relaxometry for biomedicine and advanced materials (HORIZON-MSCA-DN-2021 — FC-RELAX 101072758), 15-20 April 2024, Instituto Superior Técnico, Av. Rovisco Pais 1, Lisbon, Portugal
FC-RELAX Event Lisbon 15-17 April 2024
Madalina Ranga
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1459254
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