A 16-year-old girl presenting with calcinosis cutis and localized scleroderma subsequently developed delayed-onset idiopathic inflammatory myopathy five years after initial skin involvement. Despite the absence of typical dermatomyositis features and negative myositis-specific antibodies, whole-body MRI revealed extensive subclinical muscle inflammation. This rare clinical evolution highlights the importance of long-term surveillance in pediatric autoimmune disease and supports the role of imaging in detecting early, atypical manifestations of inflammatory myopathy.

Calcinosis Cutis and Delayed‐Onset Myositis in a Case of Suspected Localized Scleroderma: A Diagnostic and Therapeutic Challenge / Marrani, Edoardo; Gatti, Laura; Pagnini, Ilaria; Oranges, Teresa; Filippeschi, Cesare; Simonini, Gabriele. - In: PEDIATRIC DERMATOLOGY. - ISSN 0736-8046. - ELETTRONICO. - (2026), pp. 0-0. [10.1111/pde.70251]

Calcinosis Cutis and Delayed‐Onset Myositis in a Case of Suspected Localized Scleroderma: A Diagnostic and Therapeutic Challenge

Marrani, Edoardo;Gatti, Laura;Pagnini, Ilaria;Oranges, Teresa;Filippeschi, Cesare;Simonini, Gabriele
2026

Abstract

A 16-year-old girl presenting with calcinosis cutis and localized scleroderma subsequently developed delayed-onset idiopathic inflammatory myopathy five years after initial skin involvement. Despite the absence of typical dermatomyositis features and negative myositis-specific antibodies, whole-body MRI revealed extensive subclinical muscle inflammation. This rare clinical evolution highlights the importance of long-term surveillance in pediatric autoimmune disease and supports the role of imaging in detecting early, atypical manifestations of inflammatory myopathy.
2026
0
0
Marrani, Edoardo; Gatti, Laura; Pagnini, Ilaria; Oranges, Teresa; Filippeschi, Cesare; Simonini, Gabriele
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1471028
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact