We hypothesize that RV dilatation in utero may represent a red flag for myocardial frailty in the context of a genetic predisposition to DCM, which may become clinically overt following the transition to adult circulation. These observations expand the clinical spectrum of RV dilatation in the fetus and warrant specific surveillance to exclude early-onset DCM during follow-up.
Fetal Right Ventricular Dilatation and Dysfunction as a Precursor of Dilated Cardiomyopathy: A Diagnostic Pitfall and a Call for Vigilance / Bonanni, F., Cordisco, A., Calabri, G.B., Girolami, F., Olivotto, I., Favilli, S.. - In: JACC. HEART FAILURE. - ISSN 2213-1787. - ELETTRONICO. - 14:(2026), pp. 103048.0-103048.0. [10.1016/j.jchf.2026.103048]
Fetal Right Ventricular Dilatation and Dysfunction as a Precursor of Dilated Cardiomyopathy: A Diagnostic Pitfall and a Call for Vigilance
Cordisco, Adalgisa;Girolami, Francesca;Olivotto, Iacopo;Favilli, Silvia
2026
Abstract
We hypothesize that RV dilatation in utero may represent a red flag for myocardial frailty in the context of a genetic predisposition to DCM, which may become clinically overt following the transition to adult circulation. These observations expand the clinical spectrum of RV dilatation in the fetus and warrant specific surveillance to exclude early-onset DCM during follow-up.
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