Aims: The relative role of multiple determinants of left atrial volume index (LAVi) in athletes and non-athletes is not fully defined. Thus, we decided to prospectively assess the determinants of LAVi in healthy individuals and competitive athletes over a wide age range. Methods and results Four hundred and eighteen healthy individuals (mean age 41.7±15.6 years, range 16-84, 65% males, 38% competitive athletes) underwent Doppler echocardiography including assessment of LAVi by the biplane area-length method and of left ventricular (LV) diastolic function including the ratio of early diastolic peak LV inflow velocity to peak myocardial early diastolic velocity (E/e'). Mean LAVi was 32.2±9.0 mL/m 2 in the pooled population. LAVi was larger in athletes than in non-athletes (38.9±9.6 mL/m 2 vs. 28.4±5.8 mL/m 2, P , 0.0001). Conclusions: In healthy individuals LV size, competitive sport, age, and LV mass are independent determinants of LAVi. Body mass index and the E/e' ratio affect LAVi only in non-athletes. These findings may have practical implications when assessing normalcy of LA size in the clinical setting. All rights reserved. © The Author 2011.
Determinants of echocardiographic left atrial volume: Implications for normalcy / Nistri S., Galderisi M., Ballo P., Olivotto I., D'Andrea A., Pagliani L., Santoro A., Papesso B., Innelli P., Cecchi F., Mondillo S.. - In: EUROPEAN JOURNAL OF ECHOCARDIOGRAPHY. - ISSN 1525-2167. - ELETTRONICO. - 12:(2011), pp. 826-833. [10.1093/ejechocard/jer137]
Determinants of echocardiographic left atrial volume: Implications for normalcy
Olivotto I.;Cecchi F.;Mondillo S.
2011
Abstract
Aims: The relative role of multiple determinants of left atrial volume index (LAVi) in athletes and non-athletes is not fully defined. Thus, we decided to prospectively assess the determinants of LAVi in healthy individuals and competitive athletes over a wide age range. Methods and results Four hundred and eighteen healthy individuals (mean age 41.7±15.6 years, range 16-84, 65% males, 38% competitive athletes) underwent Doppler echocardiography including assessment of LAVi by the biplane area-length method and of left ventricular (LV) diastolic function including the ratio of early diastolic peak LV inflow velocity to peak myocardial early diastolic velocity (E/e'). Mean LAVi was 32.2±9.0 mL/m 2 in the pooled population. LAVi was larger in athletes than in non-athletes (38.9±9.6 mL/m 2 vs. 28.4±5.8 mL/m 2, P , 0.0001). Conclusions: In healthy individuals LV size, competitive sport, age, and LV mass are independent determinants of LAVi. Body mass index and the E/e' ratio affect LAVi only in non-athletes. These findings may have practical implications when assessing normalcy of LA size in the clinical setting. All rights reserved. © The Author 2011.
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