VIP-containing nerve cells and fibers in the human ileocecal region (pre-junctional ileum, ileocecal and cecocolonic junctions, post-junctional cecum and colon) have been evaluated by immunocytochemistry. A high density of VIP-positive neurons and nerve fibers was found in all layers of the ileum. At all colonic levels examined and at both junctions, the percentage of VIP-containing cells was higher in the submucous plexus than in the myenteric plexus. At both junctions, the muscle wall was devoid of, and the myenteric plexus extremely poor in VIP-positive nerve fibers and cells. These data suggest that motility of these junctions is not - or only to a minor extent - regulated in man by VIP-containing nerves, at variance with other gut sphincteric areas.
Distribution of VIP- immunoreactive nerve cells and fibers in the human ileocecal region / FAUSSONE-PELLEGRINI MS; S. BACCI; PANTALONE D; CORTESINI C. - In: NEUROSCIENCE LETTERS. - ISSN 0304-3940. - STAMPA. - 157:(1993), pp. 135-139.
Distribution of VIP- immunoreactive nerve cells and fibers in the human ileocecal region.
PELLEGRINI, MARIA SIMONETTA;BACCI, STEFANO;PANTALONE, DESIRE';CORTESINI, CAMILLO
1993
Abstract
VIP-containing nerve cells and fibers in the human ileocecal region (pre-junctional ileum, ileocecal and cecocolonic junctions, post-junctional cecum and colon) have been evaluated by immunocytochemistry. A high density of VIP-positive neurons and nerve fibers was found in all layers of the ileum. At all colonic levels examined and at both junctions, the percentage of VIP-containing cells was higher in the submucous plexus than in the myenteric plexus. At both junctions, the muscle wall was devoid of, and the myenteric plexus extremely poor in VIP-positive nerve fibers and cells. These data suggest that motility of these junctions is not - or only to a minor extent - regulated in man by VIP-containing nerves, at variance with other gut sphincteric areas.File | Dimensione | Formato | |
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