2,7-Dihydroxyhexahydropyrrolizine-1-carboxylic acid derivatives have been prepared in solid-phase by intermolecular 1,3-dipolar cycloaddition between an immobilised maleate or 4-hydroxycrotonate and an enantiopure 3-alkoxypyrroline N-oxide.
Solid-phase Access to Polyhydroxypyrrolizidines by 1,3-Dipolar Cycloaddition of (S)-3-Alkoxypyrroline N-oxide to Maleate and Crotonate Derivatives / F. Pisaneschi; C. Della Monica; F. M. Cordero; A. Brandi. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 43:(2002), pp. 5711-5714.
Solid-phase Access to Polyhydroxypyrrolizidines by 1,3-Dipolar Cycloaddition of (S)-3-Alkoxypyrroline N-oxide to Maleate and Crotonate Derivatives
PISANESCHI, FEDERICA;CORDERO, FRANCA MARIA;BRANDI, ALBERTO
2002
Abstract
2,7-Dihydroxyhexahydropyrrolizine-1-carboxylic acid derivatives have been prepared in solid-phase by intermolecular 1,3-dipolar cycloaddition between an immobilised maleate or 4-hydroxycrotonate and an enantiopure 3-alkoxypyrroline N-oxide.
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