Genosensor technology relying on the use of carbon and gold electrodes is reviewed. The key steps of each analytical procedure, namely DNA-probe immobilisation, hybridisation, labelling and electrochemical investigation of the surface, are discussed in detail with separate sections devoted to label-free and newly emerging magnetic assays. Special emphasis has been given to protocols that have been used with real DNA samples.
Carbon and gold electrodes as electrochemical transducers for DNA hybridisation sensors / Lucarelli, F.; Marrazza, G.; Turner A.P.F.; Mascini, M.. - In: BIOSENSORS & BIOELECTRONICS. - ISSN 0956-5663. - STAMPA. - 19 (6):(2004), pp. 515-530.
Carbon and gold electrodes as electrochemical transducers for DNA hybridisation sensors.
Lucarelli, F.;Marrazza, G.;Mascini, M.
2004
Abstract
Genosensor technology relying on the use of carbon and gold electrodes is reviewed. The key steps of each analytical procedure, namely DNA-probe immobilisation, hybridisation, labelling and electrochemical investigation of the surface, are discussed in detail with separate sections devoted to label-free and newly emerging magnetic assays. Special emphasis has been given to protocols that have been used with real DNA samples.
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