Described herein are derivatives of arylsulfonamido-substituted hydroxamic acid of formula (I) having good solubility in water and inhibitory activity of matrix metalloproteinases, useful for the preparation of pharmaceutical compositions for the treatment of diseases associated to a pathologic activity and/or an over-expression of metalloproteinases, and of cosmetic preparations having anti-ageing properties in particular for hair and
Preparation of arylsulfonamide-substituted hydroxamic acid derivatives as matrix metalloproteinases inhibitors / BERTINI I; M. FRAGAI; LO CONTE M; LUCHINAT C; NATIVI C; VENTURI C. - (2005).
Preparation of arylsulfonamide-substituted hydroxamic acid derivatives as matrix metalloproteinases inhibitors
BERTINI, IVANO;FRAGAI, MARCO;LUCHINAT, CLAUDIO;NATIVI, CRISTINA;
2005
Abstract
Described herein are derivatives of arylsulfonamido-substituted hydroxamic acid of formula (I) having good solubility in water and inhibitory activity of matrix metalloproteinases, useful for the preparation of pharmaceutical compositions for the treatment of diseases associated to a pathologic activity and/or an over-expression of metalloproteinases, and of cosmetic preparations having anti-ageing properties in particular for hair and
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